Maintaining normal FSH levels is regarded central to maintaining proper sexual and reproductive health among men and women, starting from ensuring proper pubertal development. Follicle stimulating hormone (FSH) is among the most vital of hormones in the human body and its concentration begins to rise significantly once an individual enters the teenage years. This is because during the puberty stage, FSH is secreted in copious amounts. This is found among both, boys and girls. While among boys, FSH plays a significant role in the sperm maturation process, among girls it is responsible for initiating the process of ovulation and regulating the menstrual cycle in coordination with many other hormones like progesterone, estrogen and LH.
Please note that FSH is essentially a Gonadotropin that is secreted by the anterior pituitary gland. This happens when the pituitary gland is acted upon by the Gonadotropin-releasing hormone or GnRH released by the hypothalamus. The same gland is responsible for secreting Luteinizing Hormone. The pituitary gland works in such a manner that it seeks to maintain a balance between FSH and LH levels. Similarly, FSH levels are maintained in the body in coordination with other hormones like estrogen and progesterone. Thus, normal FSH levels can be established only when FSH and the concentration of other hormones is in perfect sync with each other. This state of balance is rather necessary since the slightest of disturbances can induce unwanted health complications.
This is essentially because FSH, in coordination with LH, binds to particular receptors in testis and ovaries. Thus, these hormones directly regulate many aspects of gonadal functions such as the stimulation of sexual steroid hormones, produced by the gonads. Thus, when normal FSH levels are disturbed, a host of sexual developmental and reproductive problems are likely to surface. This includes delayed pubertal development apart from issues such as delayed ovulation, infertility and the inability to conceive apart from overall poor sexual health conditioning. For maintaining normal FSH level, a practitioner might need to recommend either FSH suppression or FSH supplementation. FSH & LH are affected by a negative feedback mechanism. For instance, the presence of Inhibin has a negative feedback on FSH only. When FSH suppression needs to be done, i.e. to decrease the amount of FSH in the body, high doses of testosterone or estrogen hormonal supplementation need to be prescribed.
A very high level of FSH in the body can also indicate an underlying case of gonadal failure. However, sometimes FSH supplementation needs to be done, particularly among young boys and girls, when delayed puberty onset is indicated. In such cases, natural or synthetic FSH supplements are provided as a hormonal booster. Please understand that this is a rather delicate kind of therapy since the slightest of mis-dosage can cause problems like Hypopituitarism or Hypothyroidism, apart from upsetting the entire hormonal balance. Normal levels of FSH are also indicative that the sexual health of the individual is fine and he/she is least likely to suffer from problems such as tumors of pituitary or gonadal tumors. The only way of ensuring that normal FSH levels are being maintained within the body is a timely and repeated FSH test that is easily available at clinical facilities.